People tired due to narcolepsy symptoms 2

“Tell me, what is the XYREM® REMS Program?”

The XYREM REMS Program: an overview.

All prescribers and patients must enroll one time in the XYREM REMS Program.1

  • Because of the risks of CNS depression, abuse, and misuse, XYREM is available only through a restricted distribution program called the XYREM REMS Program, using the central pharmacy that is specially certified. Prescribers and patients must enroll in the program.2
  • The XYREM REMS Program is designed to ensure that prescribers and patients are educated on and understand the risks and safe use conditions of XYREM and agree to follow the requirements of the XYREM REMS Program.1,2
  • The program also ensures that XYREM is dispensed from the specially certified central pharmacy.1,2

Need help? Have questions? Get answers.

For further information, visit or call |


A Nurse Case Manager is available Monday – Friday, 7 AM – 8 PM, Central Time.
A pharmacist is available 24 hours a day, 7 days a week.